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A Structured Approach to R&D Valuation and Portfolio Strategy
Introduction The process of drug development is fraught with uncertainty, requiring companies to make high-stakes decisions across a landscape defined by scientific complexity, long timelines, regulatory unpredictability, and commercial risk. Despite advances in biomedical science and access to vast datasets, many critical development and portfolio decisions continue to rely on fragmented...
QLS Technologies Company Announcement
New company delivers AI-powered portfolio modeling platform to support capital allocation, risk management and innovation in drug development Cambridge, MA--May 29, 2025--QLS Technologies LLC launched today as a spinout from QLS Advisors LLC, with a mission to apply financial engineering to foster innovation in the life sciences. As biomedicine has grown more complex, financing strategy has...
Publications
- 2024 – Portfolio Management Research – BridgeBio Case Study
- 2022 – Nature Biotechnology – Venture philanthropy in biotech
- 2022 – Journal of Multimorbidity & Comorbidity – Estimating mortality and multimorbidity
- 2021 – BIO Report – Probability of success estimates of clinical trial outcomes, 2011-2020
- 2021 – Portfolio Management Research – Financing correlated drug development portfolios
- 2021 – Patterns – Data science challenge with big pharma
- 2020 – Journal of Econometrics – Financially adaptive clinical trials via option pricing analysis
- 2019 – Harvard Data Science Review – Machine learning with statistical imputation for predicting drug approvals
- 2019 – Biostatistics – Estimation of clinical trial success rates and related parameters
- 2019 – Journal of Investment Management – Financing ovarian cancer therapeutics
- 2019 – JCO Clinical Cancer Informatics – Machine-learning forecasts of lung cancer patient outcomes
- 2017 – Nature Biotechnology – Investment returns in the biopharma industry
- 2017 – Drug Discovery Today – Accelerating university biomedical innovation
- 2015 – Science Translational Medicine – Financing rare disease therapeutics
- 2014 – Nature Biotechnology – Clinical development success rate
- MIT Project Alpha